THINK MITOCHONDRIAL DISEASE WHEN THREE
OR MORE ORGAN SYSTEMS ARE INVOLVED
Mitochondrial disease can cause any symptom in any organ at any age.
BRAIN
Developmental delays
Dementia
Neuro-psychiatric disturbances
Migraines
Autistic Features
Mental retardation
Seizures
Atypical cerebral palsy
Strokes/Stroke-like episode
EARS & EYES
Tinnitus
Hearing loss and deafness
Visual loss and blindness
Ptosis
Ophthalmoplegia
Optic atrophy
Acquired strabismus
Retinitis pigmentosa
MUSCLES
Weakness
Cramping
Dysphagia (swallowing problems)
Gastrointestinal problems
Dysmotility
Irritable bowl syndrome
Hypotonia
Muscle pain
Gastroesophogeal reflux
Diarrhoea or constipation
Pseudo-obstruction
KIDNEYS
Renal tubular acidosis or wasting
HEART
Cardiac conduction defects (heart blocks)
Cardiomyopathy
LIVER
Hypoglycemia (low blood sugar)
Liver failure
NERVES
Weakness (may be intermittent)
Absent reflexes
Fainting
Neuropathic pain
Dysautonomia - temperature instability
Other dysautonomic problems
PANCREAS & OTHER GLANDS
Diabetes and exocrine pancreatic failure (inability to make digestive enzymes)
Parathyroid failure (low calcium)
Diabetes
SYSTEMIC
Failure to gain weight
Fatigue
Unexplained vomiting
Short stature
Respiratory problems